Insights

Science, Not Wellness Theatre

Peer-reviewed research, evidence-based longevity, and clinical commentary. We cite our sources. We don't sell supplements. We don't hype peptides. We don't run unvalidated cancer blood tests. Just the science — and what it means for your health.

Latest Published 2026-04-15 · 3 min read · Topic: Longevity Science

Why Your "Biological Age" Is Already Out of Date

New 2026 research in Ageing Research Reviews shows human aging is asynchronous — different organs age at dramatically different rates within the same person. A single "biological age" number averages out what actually matters. Here's what organ-specific aging means for preventive medicine, and why the single-number test is already behind the science.

Read the full piece →
Coming soon

The Galleri Problem: What Multi-Cancer Blood Tests Actually Detect

A close look at 2025 PATHFINDER data: 39% sensitivity, 44% positive predictive value, and what that means for using Galleri-style tests in preventive medicine.

Coming soon

VO2 Max: The Longevity Biomarker Most Executives Have Never Measured

Why cardiorespiratory fitness is one of the strongest predictors of all-cause mortality — and why almost no standard executive physical measures it properly.

Coming soon

Why We Don't Sell Peptides

A clinical position on off-label peptide use — what the evidence actually supports, what it doesn't, and why Durand doesn't prescribe them.

Coming soon

The Five Biomarkers Your Annual Physical Isn't Testing

ApoB. Lp(a). hs-CRP. HbA1c patterns. Coronary artery calcium. A clinical look at what's missing from standard annual physicals — and why it matters for the next decade of your health.

Editorial standards

What You Won't Find Here

We don't publish wellness trends, supplement reviews, peptide recommendations, or fear-based marketing. Every piece cites peer-reviewed sources with DOI links. Where the evidence is uncertain, we say so. This is the editorial voice we'd want our own physicians to trust.

Interested in a Clinical Assessment?

The research is one thing. Getting the right measurements for your own health is another.